How Mantle Cell lymphoma is Diagnosed

Diagnosis of Mantle Cell Lymphoma

MCL cannot be diagnosed by symptoms alone. Diagnosis involves the microscopic examination of tissue obtained by a lymph node biopsy.

The extent of the disease or ‘staging’ should be determined in order to plan the best treatment. Tests used for staging may include the following:

  • Blood tests to assess the concentration of red cells, white cells and platelets
  • Bone marrow biopsy to identify if this is a site of the disease
  • Scans - Computerised Tomography (CT) or Magnetic Resonance Imaging (MRI), and possibly Positron Emission Tomography (PET) of the whole of your body. The images that these scans produce allow your doctor to see whether the disease is present in the deep lymph nodes, liver, spleen or anywhere else in your body.
  • Sometimes further biopsies may be required from affected parts of your body, but

These tests usually take place in a hospital but none should require an overnight stay. The test results are usually reviewed by a group of experienced healthcare professionals (a multidisciplinary team, experts in their own fields) before the diagnosis and stage of the illness is confirmed, and a course of treatment can be recommended.

The Lymphoma Association have produced a really helpful document for patients with Mantle cell Lymphoma, you can download this here:

If you suspect you have symptoms contact your GP

Plymouth Hospitals NHS Trust UKCRC Plymouth University Peninsula

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